COVID-19 Diagnosis and Treatment: What You Need to Know

If you are experiencing symptoms of COVID-19, or suspect you’ve been exposed to the virus, it’s crucial to get in touch with your healthcare provider immediately. Inform them if you have been in close proximity to anyone who has received a COVID-19 diagnosis.

In the United States, convenient at-home COVID-19 tests are readily available. You can order free tests to be delivered directly to your U.S. address, or purchase them at various retail locations such as stores, pharmacies, and online retailers. These tests are authorized or approved by the U.S. Food and Drug Administration (FDA). The FDA website provides a regularly updated list of validated tests along with their expiration dates. If you have any uncertainties or concerns, consulting your healthcare professional before purchasing a test is always a good idea.

When performing an at-home test, meticulous adherence to the provided instructions is essential. Carefully follow each step to ensure the most accurate result possible.

COVID-19 testing services are also accessible through healthcare professionals, select pharmacies and clinics, and designated community testing sites.

Here are some recommended guidelines outlining when to consider taking a COVID-19 test:

  • Symptomatic Individuals: If you are exhibiting COVID-19 symptoms, it’s advisable to get tested promptly.
  • Asymptomatic Exposure: If you’ve been exposed to the COVID-19 virus but are not showing symptoms, wait for at least five days post-exposure before taking a test.
  • Post-Illness Testing: If you had symptoms and tested positive for COVID-19 within the last 30 days, re-testing is permissible. However, if you were recently exposed to the coronavirus without symptoms, routine testing is not necessary.

Furthermore, undergoing testing before attending events or interacting with individuals at a higher risk of severe illness is a proactive measure to help curb the transmission of the virus that causes COVID-19.

COVID-19 tests typically involve collecting a sample from your nasal passage, throat, or saliva.

Two primary types of tests are utilized for COVID-19 diagnosis:

  • Molecular Tests (PCR/NAAT): These tests are designed to detect genetic material from the COVID-19 virus.

    Polymerase Chain Reaction (PCR) tests, also known as Nucleic Acid Amplification Tests (NAAT), fall under the category of molecular tests.

    PCR tests are recognized for their higher accuracy compared to antigen tests. While PCR tests can be conducted at home, they are more commonly performed by healthcare professionals and processed in laboratory settings.

  • Antigen Tests (Rapid/At-Home Tests): These tests identify viral proteins, known as antigens.

    Antigen tests are often referred to as rapid COVID-19 tests or at-home COVID-19 tests due to their quick results.

    While antigen tests are considered reliable and accurate, they are generally less sensitive than PCR tests, particularly in individuals without symptoms. If you receive a negative result from an antigen test and are concerned, it’s recommended to take another antigen test after 48 hours for greater accuracy.

Deciphering Your Test Results

A positive result from either a COVID-19 PCR or antigen test strongly indicates a COVID-19 infection. In such cases, further testing is usually unnecessary.

A negative PCR test result suggests that you most likely do not have a COVID-19 infection.

If you receive a negative antigen test result, the FDA recommends repeating the antigen test 48 hours after the initial test. Regardless of whether you have symptoms, repeating the test aids in confirming the diagnosis.

Should you test positive for COVID-19, promptly contact a healthcare professional to discuss available options and guidance.

Preventing Virus Spread While Sick

To minimize the risk of spreading the COVID-19 virus to others, it is essential to stay at home and physically separate yourself from household members as long as your symptoms are worsening. Individuals with weakened immune systems might need to extend their isolation period, depending on their specific symptoms and health history. Your healthcare professional can provide tailored advice for your situation.

If you must be around others, wearing a face mask effectively reduces the spread of the coronavirus. During this period, avoid sharing personal items like cups and towels, and if possible, utilize a separate bathroom and bedroom. Enhancing ventilation within your home can also be beneficial.

Once you experience improvement in symptoms and have been fever-free for a complete 24 hours (without using fever-reducing medication), you can resume interactions with others. However, if your fever returns or your condition deteriorates, revert to isolation until your symptoms improve and you remain fever-free without medication for 24 hours. Always prioritize the guidance of your healthcare professional.

In the five days following isolation, to further mitigate virus transmission, consider wearing a mask, practicing diligent hand hygiene, maintaining physical distance, undergoing COVID-19 testing, and improving indoor airflow. These precautions are valuable even if you tested positive but never developed symptoms.

Further Resources

Explore more information on COVID-19 Diagnosis from Mayo Clinic

Alt text: A person carefully performs a COVID-19 rapid antigen self-test at home, following the instructions for accurate sample collection and result interpretation.

Treatment Options for COVID-19

Many individuals with COVID-19 recover effectively through rest, adequate hydration, and symptom management. Over-the-counter medications can provide relief, including:

  • Fever Reducers: To manage elevated body temperature.
  • Pain Relievers: Such as ibuprofen or acetaminophen, to alleviate discomfort.
  • Cough Syrup or Medicine: To ease cough symptoms.

For individuals at an elevated risk of severe COVID-19 illness, healthcare professionals may recommend medications to prevent mild cases from progressing. These may include nirmatrelvir and ritonavir (Paxlovid), remdesivir (Veklury), or molnupiravir (Lagevrio).

Paxlovid and Lagevrio are administered orally in pill form, while Veklury is given intravenously.

In cases of severe illness, hospitalization may be necessary for comprehensive care.

Hospital Treatment for Severe Cases

Hospital care for severe COVID-19 is tailored based on the patient’s immune system response and oxygen support requirements.

Supplemental oxygen may be administered via nasal tubes. In some cases, mechanical ventilation, involving a tube inserted into the airway to assist breathing, becomes necessary. For critical situations, Extracorporeal Membrane Oxygenation (ECMO) may be employed to replicate the functions of the heart and lungs.

Medications for severe COVID-19 may include remdesivir, baricitinib (Olumiant), tocilizumab (Actemra), or corticosteroids like dexamethasone.

Baricitinib is available as a pill, tocilizumab as an injection, and dexamethasone can be administered either orally or intravenously.

Convalescent plasma, derived from blood donated by recovered COVID-19 patients, represents another potential treatment avenue. This plasma, rich in antibodies, may aid individuals with compromised immune systems in their COVID-19 recovery.

Further Resources

Learn more about COVID-19 Treatment from Mayo Clinic

Alt text: In a hospital room, a doctor compassionately discusses COVID-19 treatment options with a concerned patient, ensuring clear communication and addressing questions.

Stay Informed with Mayo Clinic

Sign up for free updates and stay informed about the latest research, health advice, and expertise in health management. Click here for an email preview.

Clinical Trials

Explore Mayo Clinic studies investigating innovative treatments, interventions, and diagnostic methods for COVID-19 prevention, detection, treatment, and management.

Lifestyle and Home Care

If you have COVID-19, prioritizing rest, fluid intake, and symptom monitoring is crucial. Over-the-counter medicines can help manage pain, fever, and cough.

While isolating, maintaining engagement and supporting your body’s recovery process is important. Consider these helpful measures:

  • Consume nutritious meals.
  • Ensure adequate sleep.
  • Practice relaxation techniques.
  • Engage in enjoyable activities.
  • Connect with loved ones through phone or video calls.

Individuals with COVID-19 or caregivers may experience heightened stress, depression, or anxiety. If you or someone you know needs support, reach out to a healthcare professional and consider seeking a referral to a mental health specialist.

Related Information Resources

Access related information on COVID-19 and overall health from Mayo Clinic

Preparing for Your Medical Appointment

For COVID-19 related medical care, you can start by consulting your primary healthcare professional, or you might be directly referred to an infectious disease specialist.

Here’s guidance to help you prepare for your appointment:

What You Can Do Beforehand

When scheduling your appointment, inquire if there are any pre-appointment instructions. Compile a list of:

  • Your Symptoms: Include all symptoms, even those seemingly unrelated to your primary concern.
  • Recent Travel History: Note any recent travels, including international trips.
  • Key Personal Information: Include significant stressors, recent life changes, and relevant family medical history.
  • Current Medications and Supplements: List all medicines, vitamins, and supplements you are taking, including dosages.
  • Questions for Your Doctor: Prepare a list of questions to ask your healthcare provider.

If possible, bring a family member or friend to assist with information retention. Limit accompanying individuals to one or two and check for visitor restrictions at your clinic or hospital beforehand.

Essential questions to ask your healthcare team include:

  • How likely is COVID-19 causing my symptoms?
  • What are other potential causes for my symptoms?
  • What tests are necessary?
  • What treatment approach do you recommend?
  • Are there any activity restrictions I should follow?
  • Should I consult a specialist?

What to Expect from Your Doctor

Your healthcare professional will likely ask you several questions, such as:

  • When did your symptoms start?
  • Where have you traveled recently?
  • Who have you been in close contact with?
  • How severe are your symptoms?

Authored by Mayo Clinic Staff

Comments

No comments yet. Why don’t you start the discussion?

Leave a Reply

Your email address will not be published. Required fields are marked *