The American College of Physicians (ACP) provides regularly updated, rapid practice points to assist primary care physicians in the diagnosis and treatment of COVID-19. These guidelines are designed to be living documents, evolving with the latest evidence and clinical understanding of the virus. Below is a compilation of key practice points, offering a concise overview for healthcare professionals.
Outpatient Treatment of Confirmed COVID-19
For managing confirmed COVID-19 cases in outpatient settings, the ACP has released several versions of practice points to keep clinicians informed with the most current recommendations.
- July 2024 Update (Version 2): This latest update focuses on the most recent advancements in outpatient treatment strategies. Full text
- September 2023 (Version 2): Providing guidance on outpatient care, this version reflects the clinical best practices at the time of publication. Full text
- November 2022 (Version 1): This initial version addressed the outpatient treatment of mild to moderate COVID-19, setting the foundation for subsequent updates. Full text
Understanding Antibody Response and Natural Immunity Post-SARS-CoV-2 Infection
The ACP has also provided practice points to clarify the antibody response and the immunity conferred by natural infection of SARS-CoV-2, crucial for primary care diagnosis and patient counseling.
- January 2022 (Version 2): This version updates the understanding of antibody responses and natural immunity as more data became available. Full text
- March 2021 (Version 1): The first version established the baseline knowledge regarding antibody responses and natural immunity following COVID-19 infection. Full text
Remdesivir in the Treatment of COVID-19
The use of Remdesivir has been a significant point of discussion in COVID-19 treatment. The ACP has issued multiple updates to guide clinicians on its appropriate use.
- February 2022 Update 3 (Version 2): This update provides the latest recommendations on Remdesivir use, reflecting evolving clinical experiences. Full text
- October 2021 Update 2 (Version 2): An interim update to refine guidance on Remdesivir based on new data. Full text
- July 2021 Update 1 (Version 2): Early update adjusting recommendations for Remdesivir as understanding grew. Full text
- February 2021 (Version 2): This version offered a consolidated view on Remdesivir’s role in treatment at the time. Full text
- October 2020 (Version 1): The initial practice points on whether Remdesivir should be used for COVID-19 treatment. Full text
Chloroquine and Hydroxychloroquine in COVID-19 Prophylaxis and Treatment
The ACP addressed the controversial topic of using chloroquine and hydroxychloroquine for COVID-19, providing crucial guidance during a period of uncertainty.
- July 2020 Update 2: Further guidance on the use of chloroquine or hydroxychloroquine, either alone or with azithromycin. Full text
- June 2020 Update 1: An update to the initial recommendations regarding these medications. Full text
- May 2020 (Version 1): The first practice points addressing the use of chloroquine and hydroxychloroquine for COVID-19. Full text
Mask Usage for COVID-19 Prevention
Guidance on mask usage in healthcare and community settings has been vital in primary care diagnosis and prevention strategies. The ACP offered practice points on this topic as well.
- October 2020 Update 1: Updated recommendations on the use of N95, surgical, and cloth masks. Full text
- June 2020 (Version 1): Initial practice points on mask usage to prevent COVID-19 in various settings. Full text
These living, rapid practice points from the American College of Physicians serve as essential resources for primary care physicians navigating the complexities of COVID-19 diagnosis, treatment, and prevention. It is recommended to consult the full text of each guideline for detailed information and the most current recommendations.
